49th District — Southern Orange County and Northern San Diego
Open seat Issa
The Republican vote share in the primary — around 49% — suggests Democrats have a strong chance of flipping this seat, soon to be vacated by Issa, who won reelection in 2016 by around 1,600 votes. His potential GOP replacement, Diane Harkey, the state tax board chairman who won first place in the primary, has better name recognition than her Democratic opponent, attorney Mike Levin. Levin is certain to have plenty of Democratic support and money behind him as the party eyes this seat as one of its best pickup opportunities.

Key votes:

For: Obamacare repeal  For: GOP tax plan